HRID274615

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

HCID10053461

5-[4'-(Bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-1H-tetrazole

C33H25BrN4

结构：CCCCc1nc2cscc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

HCID53848289

未命名化合物

PRODUCTS

生成物

结构：CCCCc1nc2cscc2n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

HCID20093423

未命名化合物

PROCEDURE

实验过程

This Step A compound can be prepared in a similar fashion to the preparation of 4'-[(2-butyl-1H-thieno[3,4-d]imidazol-1-yl)methyl][1,1'-biphenyl]-2-carboxylic acid t-butyl ester (Example 1, Step B) except that the alkylating agent used can be 2'-(N-triphenylmethyltetrazol-5-yl)biphen-4-yl methyl bromide in place of t-butyl-4'-bromomethylbiphenyl-2-carboxylate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3d03b90163e04e9283b67b0df9fddf47
来源数据集: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05389660
来源说明: uspto-grants-1995_02

反应 SMILES

C(O[C:6]([C:8]1[C:9]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][N:21]3[C:25]4=[CH:26][S:27][CH:28]=[C:24]4[N:23]=[C:22]3[CH2:29][CH2:30][CH2:31][CH3:32])=[CH:16][CH:15]=2)=[CH:10][CH:11]=[CH:12][CH:13]=1)=O)(C)(C)C.[C:33]1([C:39]([C:65]2[CH:70]=[CH:69][CH:68]=[CH:67][CH:66]=2)([C:59]2[CH:64]=[CH:63][CH:62]=[CH:61][CH:60]=2)[N:40]2C(C3C=CC=CC=3C3C=CC(CBr)=CC=3)=[N:43][N:42]=[N:41]2)[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1>>[CH2:29]([C:22]1[N:21]([CH2:20][C:17]2[CH:18]=[CH:19][C:14]([C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[C:6]3[N:40]([C:39]([C:33]4[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=4)([C:65]4[CH:66]=[CH:67][CH:68]=[CH:69][CH:70]=4)[C:59]4[CH:60]=[CH:61][CH:62]=[CH:63][CH:64]=4)[N:41]=[N:42][N:43]=3)=[CH:15][CH:16]=2)[C:25]2=[CH:26][S:27][CH:28]=[C:24]2[N:23]=1)[CH2:30][CH2:31][CH3:32]