HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(7-Methoxynaphthalen-1-yl)acetic acid | HCID 13570105 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-(7-Methoxynaphthalen-1-yl)acetyl chloride | HCID 19385766 | — |
Reaction Steps
The 7-methoxynaphth-1-ylacetic acid obtained above is dissolved, while warm, in 300 cm3 of chloroform. The mixture is heated to reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness, yielding an oil which crystallises by cooling. The resulting residue is used as such in the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389683 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-68b8a011210c4d8fbc1f976d53140819 |
| Source note | uspto-grants-1995_02 |