HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl bromide → Ethyl 2,2-dimethylpent-4-ynoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | 2-Bromo-2-methylpropanoic acid | HCID 74924 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | Ethyl 2,2-dimethylpent-4-ynoate | HCID 14459632 | — |
Reaction Steps
Amounts used: 14.7 ml (0.1 m, 19.5 g) of bromoisobutyric acid, 75 ml of 1.6M n-butyllithium solution in n-hexane, 40 ml of tetrahydrofuran and 17.85 g of propargylbromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE034865 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-31880714769c42a4ad0d2ffab5f3c039 |
| Source note | uspto-grants-1995_02 |