Acetonitrile → HCID 20081759, compound

Participants

Reaction Steps

To a solution of the product of Step B (0.53 g, 1.38 mmol) in dry THF (10 mL) were added Ph3P (0.49 g, 2.06 mmol), CBr4 (0.69 g, 2.06 mmol) and CH3CN (2 mL), and the mixture was stirred at room temperature for 14 h. At the end of this period, the reaction mixture was concentrated in vacuo to provide an oil, which was then purified by flash chromatography on silica-gel using ethyl acetate-hexane (1:9) to provide the titled product as a thick colorless oil (0.57 g).

Provenance & Evidence