Formic Acid → HCID 178428637, compound

HRID 274969Notes

Reaction equation

HRID 274969 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([NH:19][S:20]([C:23]2[CH:32]=[CH:31][C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[CH:24]=2)(=[O:22])=[O:21])[C:10]([N:12]2[CH2:17][CH2:16][CH:15]([CH3:18])[CH2:14][CH2:13]2)=[O:11])=[CH:4][C:3]=1[N+:33]([O-])=O.[CH:36](O)=O>[Pd]>[NH:1]1[C:2]2[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([NH:19][S:20]([C:23]3[CH:32]=[CH:31][C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH:24]=3)(=[O:22])=[O:21])[C:10]([N:12]3[CH2:17][CH2:16][CH:15]([CH3:18])[CH2:14][CH2:13]3)=[O:11])=[CH:4][C:3]=2[N:33]=[CH:36]1

Participants

4

Reactant 2

HCID 284Formic AcidHCID 20089094HCID 20089094, compound

Product 1

HCID 178428637HCID 178428637, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Prepared from N-[1-((4-amino-3-nitro-phenyl)-methyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-naphthalene-2sulphonamide and cyclising with formic acid in the presence of palladium/charcoal analogously to Example 1.

Sources & evidence

ORD record
ord-139ff33baf7d4b5cb6271b98f09f279e
Source dataset
uspto-grants-1995_02
Patent number
US05391556

Reaction notes

Loading…