Sodium Hydroxide → HCID 178428651, compound

HRID 274978Notes

Reaction equation

[NH2:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([S:9]([NH:12][CH:13]([CH2:28][C:29]2[CH:37]=[CH:36][C:32]3[NH:33][CH:34]=[N:35][C:31]=3[CH:30]=2)[C:14]([N:16]2[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH:17]2[C:23]([O:25]CC)=[O:24])=[O:15])(=[O:11])=[O:10])=[CH:4][C:3]=1[Cl:38].[OH-].[Na+]>>[NH2:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([S:9]([NH:12][CH:13]([CH2:28][C:29]2[CH:37]=[CH:36][C:32]3[NH:33][CH:34]=[N:35][C:31]=3[CH:30]=2)[C:14]([N:16]2[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH:17]2[C:23]([OH:25])=[O:24])=[O:15])(=[O:10])=[O:11])=[CH:4][C:3]=1[Cl:38]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 178468853HCID 178468853, compound

Product 1

HCID 178428651HCID 178428651, compound

Procedure

Prepared by hydrolysis of 4-amino-N-[1-(1H-benzimidazol-5-yl-methyl)-2-(2-carbethoxy-4-methyl-piperidin-1-yl)-2-oxo-ethyl]-3,5-dichloro-benzenesulphonamide in the presence of 1N sodium hydroxide solution analogously to Example 24.

Sources & evidence

ORD record: ord-cd0afb23c3ed46e69197f191ff8cff29
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05391556

Reaction notes

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