Sodium Hydroxide → HCID 178507842, compound

HRID 274980Notes

Reaction equation

[NH2:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([S:9]([NH:12][CH:13]([CH2:27][C:28]2[CH:36]=[CH:35][C:31]3[NH:32][CH:33]=[N:34][C:30]=3[CH:29]=2)[C:14]([N:16]2[CH2:21][CH2:20][CH:19]([C:22]([O:24]CC)=[O:23])[CH2:18][CH2:17]2)=[O:15])(=[O:11])=[O:10])=[CH:4][C:3]=1[Cl:37].[OH-].[Na+]>>[NH2:1][C:2]1[C:3]([Cl:37])=[CH:4][C:5]([S:9]([NH:12][CH:13]([CH2:27][C:28]2[CH:36]=[CH:35][C:31]3[NH:32][CH:33]=[N:34][C:30]=3[CH:29]=2)[C:14]([N:16]2[CH2:17][CH2:18][CH:19]([C:22]([OH:24])=[O:23])[CH2:20][CH2:21]2)=[O:15])(=[O:10])=[O:11])=[CH:6][C:7]=1[Cl:8]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 178469246HCID 178469246, compound

Product 1

HCID 178507842HCID 178507842, compound

Procedure

Prepared from 4-amino-N-[1-(1H-benzimidazol-5-yl-methyl)-2-(4-carbethoxy-piperidin-1-yl)-2-oxo-ethyl]-3,5-dichloro-benzenesulphonamide and 1N sodium hydroxide solution analogously to Example 24.

Sources & evidence

ORD record: ord-93ba43ccd7ff4f559ff3150dc1560ae4
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05391556

Reaction notes

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