Benzyloxyamine hydrochloride → HCID 85225306, compound

HRID 275001Notes

Reaction equation

HRID 275001 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:10]2[C:11](=[O:18])[N:12]([CH3:17])[CH2:13][CH2:14][C:15](=O)[C:9]=2[CH:8]=[CH:7]1.C([O-])(=O)C.[Na+].Cl.[CH2:25]([O:32][NH2:33])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>CO>[CH2:25]([O:32][N:33]=[C:15]1[CH2:14][CH2:13][N:12]([CH3:17])[C:11](=[O:18])[C:10]2[N:6]([CH2:5][CH2:4][CH2:3][CH2:2][Cl:1])[CH:7]=[CH:8][C:9]1=2)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

5

Reactant 3

HCID 102312Benzyloxyamine hydrochlorideHCID 517045Sodium AcetateHCID 10707051HCID 10707051, compound

Product 1

HCID 85225306HCID 85225306, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A suspension of 13.44 g (50 mmol) of Compound 23 obtained in Example 14, 8.20 g (100 mmol) of sodium acetate and 15.96 g (100 mmol) of O-benzylhydroxylamine hydrochloride in 250 ml of methanol was stirred for 4 hours at room temperature.

Sources & evidence

ORD record
ord-9d6ed833ff3a4ac2a3d1cbaa2bfee1b2
Source dataset
uspto-grants-1995_02
Patent number
US05391731

Reaction notes

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