HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 275016Generated: October 26, 2026
Triethyl phosphite → 6-Diethylphosphono-2,2-dimethyl-2H-chromene
https://huagongshe.com/reaction/275016
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 6-Bromo-2,2-dimethyl-2H-chromene | HCID 11770533 | — |
| Catalyst | Nickel Dichloride | HCID 24385 | — |
| Product | 6-Diethylphosphono-2,2-dimethyl-2H-chromene | HCID 15614166 | — |
Reaction Steps
16 g of 6-bromo-2,2-dimethyl-2H-chromene are dissolved in 100 ml of triethyl phosphite. 2 g of nickel chloride are added and the mixture is refluxed at 180° C. for 24 hours in an autoclave. After the remaining triethyl phosphite has been concentrated, the expected product distills at 130°-140° C. under 0.1 mm Hg. 11.5 g are collected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05391751 |
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| Source dataset | uspto-grants-1995_02 |
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| ORD ID | ord-33d77c441d1e4603a6b6341c3fc08971 |
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| Source note | uspto-grants-1995_02 |
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