反应详情

A 500 ml, 3-necked flask equipped with a mechanical stirrer, a reflux condenser with nitrogen outlet and a thermometer was charged with 24.4 g (0.2 mole of 95 percent) of 5-amino-3-mercapto-1,2,4-triazole and 140 ml of formic acid. The mixture was heated to reflux with stirring for 4 hours and allowed to cool to room temperature. The solids present were collected by filtration, washed with water, and dried to obtain 28.2 g (98 percent of theory) of the title compound as a white solid, m.p. 260°-262° C. The infrared spectrum was consistent with the assigned structure, having a carbonyl stretch at 1700 cm-1, as was the mass spectrum, having a parent peak at 144 (M+).

1. customA 500 ml, 3-necked flask equipped with a mechanical stirrer, a reflux condenser with nitrogen outlet
2. temperatureThe mixture was heated
3. temperatureto reflux
4. filtrationThe solids present were collected by filtration
5. washwashed with water
6. customdried