反应详情

1 g (3.62 mmol) of 2-fluoro-naphthacene-5,12-dione, 0.89 g (5.43 mmol) of benzenesulfinic acid sodium salt (sodium benzenesulfinate) and 10 ml of DMSO are stirred at 100° C, for 3 hours. After cooling, the mixture is poured onto water. The crystals are filtered off and dissolved in THF/toluene. The solution is dried over sodium sulfate and evaporated. The residue is recrystallized from THF/toluene/pentane. Yield: 1.35 g (94%), melting point >260° C.

1. temperatureAfter cooling
2. additionthe mixture is poured onto water
3. filtrationThe crystals are filtered off
4. dissolutiondissolved in THF/toluene
5. dry with materialThe solution is dried over sodium sulfate
6. customevaporated
7. customThe residue is recrystallized from THF/toluene/pentane