HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,3-Dimethoxy-naphthacene-5,12-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,3-Difluoronaphthacene-5,12-dione | HCID 20089834 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2,3-Dimethoxy-naphthacene-5,12-dione | HCID 11174575 | — |
Reaction Steps
1 g (3.4 mmol) of 2,3-difluoro-naphthacene-5,12-dione, 0.94 g (6.8 mmol) of K2CO3, 2.18 g of methanol and 20 ml of DMSO are stirred at 110° C. for 22 hours. The mixture is poured onto dilute hydrochloric acid. The product is filtered off, washed four times with water, dried and recrystallized from CH2Cl2 /pentane; yield 0.72 g (67%); melting point >250° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05391749 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-e5097bd68377463983c1e1c315f75eae |
| Source note | uspto-grants-1995_02 |