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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27515Generated: October 27, 2026

3-[(2-Aminoethyl)thiomethyl]pyridazine → N-nitro-N'-[2-(3-pyridazinylmethylthio)ethyl)guanidine

https://huagongshe.com/reaction/27515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(2-Aminoethyl)thiomethyl]pyridazineHCID 20242505—
ReactantN-Nitro-S-methylisothioureaHCID 135927615—
ProductN-nitro-N'-[2-(3-pyridazinylmethylthio)ethyl)guanidineHCID 178512217—

Reaction Steps

Reaction of 3-[(2-aminoethyl)thiomethyl]-pyridazine with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(3-pyridazinylmethylthio)ethyl]guanidine. Similarly, by the procedure of Example 2(iii), there is obtained N-methyl-N'-nitro-N"-[2-(3-pyridazinylmethylthio)ethyl]-guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04221802
Source datasetuspto-grants-1980_09
ORD IDord-11d198f4b413447f81bbe156e0edcc63
Source noteuspto-grants-1980_09