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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27519Generated: October 25, 2026

Ethylenediamine → N-(2-pyrimidylmethyl)ethylenediamine

https://huagongshe.com/reaction/27519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
ReactantThionyl ChlorideHCID 24386—
Reactant2-PyrimidinemethanolHCID 2763024—
Reactant2-(Chloromethyl)pyrimidineHCID 12877371—
ProductN-(2-pyrimidylmethyl)ethylenediamineHCID 20557649—

Reaction Steps

By the procedure of Example 34, ethylenediamine is reacted with 2-chloromethylpyrimidine, prepared by treating 2-hydroxymethylpyrimidine with thionyl chloride, to give N-(2-pyrimidylmethyl)ethylenediamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04221802
Source datasetuspto-grants-1980_09
ORD IDord-c0e27ad025a84aa6ab26514471d15a49
Source noteuspto-grants-1980_09