HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)pyridine → 5,6a(R),7,8,9,9a(S)-Hexahydro-2,5-dimethyl-3-(4-pyridylmethyl)-cyclopent[4,5]imidazo[2,1-b]purin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)pyridine | HCID 74571 | — |
| Reactant | 2,5-dimethyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclopenta[4,5]imidazo[2,1-b]purin-4-one | HCID 10776762 | — |
| Product | 5,6a(R),7,8,9,9a(S)-Hexahydro-2,5-dimethyl-3-(4-pyridylmethyl)-cyclopent[4,5]imidazo[2,1-b]purin-4(3H)-one | HCID 18659363 | — |
Reaction Steps
Treat 5,6a(R),7,8,9,9a(S)-hexahydro-2,5-dimethylcyclopent[4,5]imidazo[2,1-b]purin-4(3H)-one from Example 19a with 4-chloromethyl pyridine in accordance with Example 47 to give the title compound as a powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05393755 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-62871db740c9456b9ee103263f025b56 |
| Source note | uspto-grants-1995_02 |