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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27533Generated: October 30, 2026

Ethylamine → N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine

https://huagongshe.com/reaction/27533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant2-[(Thiazol-2-yl)methylthio]ethylamineHCID 12923403—
ReactantN-cyano-N'-[2-(2-thiazolylmethyl-thio)ethyl]-S-methylisothioureaHCID 20427996—
ProductN-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidineHCID 54127424—

Reaction Steps

Reaction of N-cyano-N'-[2-(2-thiazolylmethylthio)ethyl]-S-methylisothiourea, prepared from 2-[(2-aminoethyl)thiomethyl]thiazole by the procedure of Example 3(c)(i), with ethylamine by the procedure of Example 4 gives N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04221802
Source datasetuspto-grants-1980_09
ORD IDord-96f1cfe3ee2b4c429769ab443d725aa3
Source noteuspto-grants-1980_09