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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27545Generated: October 26, 2026

Ethylamine → N-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidine

https://huagongshe.com/reaction/27545

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant2-{[(1,2-Thiazol-3-yl)methyl]sulfanyl}ethan-1-amineHCID 12951537—
ReactantN-cyano-N'-[2-(3isothiazolylmethylthio)ethyl]-S-methylisothioureaHCID 20567647—
ProductN-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidineHCID 54273441—

Reaction Steps

Reacting N-cyano-N'-[2-(3-isothiazolylmethylthio)ethyl]-S-methylisothiourea, prepared from 3-[(2-aminoethyl)thiomethyl]isothiazole by the procedure of Example 3(c)(i), with ethylamine by the procedure of Example 4 gives N-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04221802
Source datasetuspto-grants-1980_09
ORD IDord-a7e69908d06246fe84c2dbb3b4350db2
Source noteuspto-grants-1980_09