Boron tribromide → N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester

HRID 275524Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:21])[C@H:5]([CH2:9][C:10]1[C:15]([I:16])=[CH:14][C:13]([O:17]C)=[C:12]([O:19]C)[CH:11]=1)[NH:6][CH:7]=[O:8])[CH3:2].B(Br)(Br)Br>>[CH2:1]([O:3][C:4](=[O:21])[C@H:5]([CH2:9][C:10]1[C:15]([I:16])=[CH:14][C:13]([OH:17])=[C:12]([OH:19])[CH:11]=1)[NH:6][CH:7]=[O:8])[CH3:2]

Participants

Reactant 2

HCID 25134Boron tribromide

HCID 11122367N-formyl-3,4-dimethoxy-6-iodo-L-phenylalanine ethyl ester

Product 1

HCID 10937745N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester

Procedure

exposing the product of step b) above to BBr3 to form N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester,

Sources & evidence

ORD record: ord-d4221d74746c4a498b8a8d2e8e377504
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05393908

Reaction notes

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