Isobutyryl chloride → HCID 53777700, compound

Participants

Reaction Steps

A solution of 0.82 g (0.01 mole) of sodium acetate in 7 mL H2O is added to a solution of 1.08 g (0. 0033 mole) of 2,6-bis (1,1-dimethylethyl)-4-[(hydroxyamino)phenylmethyl]phenol in 30 mL dioxane. Isobutyryl chloride (0.51 g, 0. 00477 mole) is added dropwise and the mixture is stirred at room temperature for 17 hours. Water (25 mL) is added to the mixture and the solid material is filtered off and washed with water. After drying it is recrystallized from Et2O-n-hexane to give off-white crystals, 0.477 g (36%), m.p. 179°-180° C.

Provenance & Evidence