HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylene Glycol Monoethyl Ether → Benzyl rac-alpha-[[[1-[[2-(2-ethoxyethoxy)ethoxy]carbonyl]-1-methylethyl]sulfonyl]methyl]hydrocinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| Reactant | (RS)-2-[[2-[(Benzyloxy)carbonyl]-3-phenylpropyl]sulfonyl]-2-methylpropionyl chloride | HCID 20088482 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Benzyl rac-alpha-[[[1-[[2-(2-ethoxyethoxy)ethoxy]carbonyl]-1-methylethyl]sulfonyl]methyl]hydrocinnamate | HCID 54520543 | — |
Reaction Steps
In an analogous manner to that of Example 2, paragraph (c), by reacting (RS)-2-[[2-[(benzyloxy)carbonyl]-3-phenylpropyl]sulfonyl]-2-methylpropionyl chloride and diethylene glycol monoethyl ether in pyridine there was obtained benzyl rac-α-[[[1-[[2-(2-ethoxyethoxy)ethoxy]carbonyl]-1-methylethyl]sulfonyl]methyl]hydrocinnamate as a colourless oil, MS: 385 (M-COObenzyl)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05393875 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-51d0dce3f47d4a25bb4eaa964b16f1d1 |
| Source note | uspto-grants-1995_02 |