Isopropyl isocyanate → HCID 53999989, compound

Participants

Reaction Steps

A solution of 1.0 g (2.56 mmol) of benzyl rac-α-[[(2-hydroxy-1,1-dimethylethyl)sulfonyl]methyl]hydrocinnamate and 0.97 g (10.24 mmol) of isopropyl isocyanate in 20 ml of dry toluene was heated to 100o for 4 hours. Subsequently, the reaction solution was evaporated under reduced pressure. The benzyl rac-α-[[[2-[(isopropylcarbamoyl)oxy]-1,1-dimethylethyl]sulfonyl]methyl]hydrocinnamate was obtained in quantitative yield as a yellowish oil, MS: 384 (M-benzyl)+.

Provenance & Evidence