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HRID275620

反应详情

EQUATION

反应方程式

HRID 275620 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)NC(Cc1cccs1)C(=O)O
HCID5035100

N-Boc-beta-(2-thienyl)-DL-alanine

C12H17NO4S

结构：N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1
HCID14930738

未命名化合物

PRODUCTS

生成物

1
结构：NC(Cc1cccs1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1
HCID57152908

未命名化合物

PROCEDURE

实验过程

In an analogous manner to that described above, by the condensation of rac-α-(tert-butoxyformamido)-3-(thiophen-2-yl)propionic acid [Pol. J. Chem. 54(11-12), 2225 (1980)] and (1S,2R,3S)-3-amino-4-cyclohexyl-1-cyclopropyl-1,2-butanediol followed by acidic hydrolysis there was obtained (RS)-α-amino-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-3-(thiophen-2-yl)propionamide, MS: 381 (M+H)+ as a colourless foam.

WORKUP

后处理

  1. customfollowed by acidic hydrolysis there