Diglycolamine → HCID 86748489, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 6, paragraphs (a) to (c), starting from 2-mercaptoisobutyric acid and ethyl 2-benzylacrylate there was obtained (RS)-2-[[2-[(ethoxy)carbonyl]-3-phenylpropyl]sulfonyl]-2-methylpropionic acid, reaction of which 2-(2-aminoethoxy)ethanol and subsequent enzymatic hydrolysis of the resulting ethyl ester yielded (S/R=9/1 )-α-[[[1-[[2-(2-hydroxyethoxy)ethyl]carbamoyl]-1-methylethyl]sulfonyl]methyl]hydrocinnamic acid, MS: 401.9 (M+H)+, as a colourless oil.

Provenance & Evidence