Methyl isothiocyanate → HCID 178483804, compound

HRID 27571Notes

Reaction equation

HRID 27571 reaction equation
NC[CH2:3][CH2:4][NH:5][CH2:6][C:7]1[NH:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.[CH3:16][N:17]=[C:18]=S.N1C2C=CC=CC=2NC=1CNC[CH2:32][CH2:33][NH:34][C:35]([NH:38][C:39]#[N:40])=[N:36]C>>[N:8]1[C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[NH:11][C:7]=1[CH2:6][NH:5][CH2:4][CH2:3][NH:36][C:35]([NH:38][C:39]#[N:40])=[N:34][CH2:33][CH2:32][N:17]([CH3:18])[CH3:16]

Participants

4

Reactant 3

HCID 11167Methyl isothiocyanateHCID 20567598HCID 20567598, compoundHCID 53702203HCID 53702203, compound

Product 1

HCID 178483804HCID 178483804, compound

Procedure

Using in the above procedure, 2-[(3-aminopropyl)aminomethyl]benzimidazole (prepared by reacting 2-chloromethylbenzimidazole with 1,3-diaminopropane) and methyl isothiocyanate, the product is N-[3-(2-benzimidazolylmethylamino)propyl]-N'-cyano-N"-methylguanidine.

Sources & evidence

ORD record
ord-6460ff36ef3548b0b6b91bebdf1b5c7c
Source dataset
uspto-grants-1980_09
Patent number
US04221802

Reaction notes

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