HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-[2-(2-(2-Benzimidazolyl)ethylamino)ethyl]-N'-cyano-N"-methylguanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 1-Cyano-2,3-dimethylisothiourea | HCID 111103 | — |
| Reactant | 2-(2-Chloroethyl)benzimidazole | HCID 12216288 | — |
| Reactant | N-[2-(2-benzimidazolyl)ethyl]ethylenediamine | HCID 20567701 | — |
| Product | N-[2-(2-(2-Benzimidazolyl)ethylamino)ethyl]-N'-cyano-N"-methylguanidine | HCID 53646889 | — |
Reaction Steps
Reacting 2-(2-chloroethyl)benzimidazole with ethylenediamine by the procedure of Example 34, then reacting one resulting N-[2-(2-benzimidazolyl)ethyl]-ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedure of Example 3(a) gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221802 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-592f203ddd2a44a8b806b593e79f9a9e |
| Source note | uspto-grants-1980_09 |