HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(pyridin-4-yl)-1H-indole → 2-[1-[2-(Indan-2-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-1h-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(pyridin-4-yl)-1H-indole | HCID 2771689 | — |
| Reactant | 2-(2-Iodoethyl)indane | HCID 18545833 | — |
| Product | 2-[1-[2-(Indan-2-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-1h-indole | HCID 18545916 | — |
Reaction Steps
Prepared from 27a and 24a. Mp 175-176 C. 1H NMR (CDCl3) δ1.75-1.85 (m, 2H), 2.45-2.55 (m, 1H), 2.55-2.60 (m, 2H), 2.60-2.70 (m, 4H), 2.70-2.80 (m, 2H), 3.05-3.15 (m, 2H), 3.25 (broad s, 2H), 6.05 (broad s, 1H), 6.45 (s, 1H), 7.05 (t, 1H), 7.10-7.25 (m, 5H), 7.35 (d, 1H), 7.55 (d, 1H), 8.10 (broad s, 1H). MS m/z (%): 343 (MH+, 8%), 174 (32%), 143 (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06352988B2 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-1fd71c60c9ad4c5682c8e9a620d9e500 |
| Source note | uspto-grants-2002_03 |