HuagongsheHuagongshe Chemistry Print Report · For research reference only
Rubitecan → 9-Aminocamptothecin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Rubitecan | HCID 472335 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 9-Aminocamptothecin | HCID 72402 | — |
Reaction Steps
As a specific example, approximately 0.5 g of the 9-nitrocamptothecin derivatives can be mixed with about 100 mg of iron powder and 20 ml of 10% HCl to form the 9-aminocamptothecin derivative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06352996B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-c11bf889a4b0456b843c0333be138537 |
| Source note | uspto-grants-2002_03 |