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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 275731Generated: November 3, 2026

Ethylamine hydrochloride → 6,7-Dimethoxy-2-ethylamino-4-(3-nitrophenyl)quinazoline

https://huagongshe.com/reaction/275731

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamine hydrochlorideHCID 11198—
Reactant2-Chloro-6,7-dimethoxy-4-(3-nitrophenyl)quinazolineHCID 12150398—
Product6,7-Dimethoxy-2-ethylamino-4-(3-nitrophenyl)quinazolineHCID 1215040235.7%

Reaction Steps

Starting from 500 mg 2-chloro-6,7-dimethoxy-4-(3-nitrophenyl)quinazoline and 1.18 g ethylamine hydrochloride, 183 mg of the title compound was obtained as yellow crystals in the same manner as in Production Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06352989B1
Source datasetuspto-grants-2002_03
ORD IDord-25e4fe74ff984ab28f5ed6b958379bdb
Source noteuspto-grants-2002_03