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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 275793Generated: October 26, 2026

1-Bromopropane → 7-Methoxy-3-propyl-2-trifluoromethylbenzimidazole

https://huagongshe.com/reaction/275793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BromopropaneHCID 7840—
ReactantHCID 178488964HCID 178488964—
Product7-Methoxy-3-propyl-2-trifluoromethylbenzimidazoleHCID 18316637—

Reaction Steps

Prepared from 4-methoxy-2-trifluoromethylbenzimidazole (2.4 g) and propyl bromide (3.02 ml). Purification by flash chromatography on silica eluting with 15% ethyl acetate in hexane gave the title compound as a white solid (2.03 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06353010B1
Source datasetuspto-grants-2002_03
ORD IDord-3768b69c0a5644d48eb12c0816af51a4
Source noteuspto-grants-2002_03