Potassium Carbonate → HCID 59878880, compound

Participants

Reaction Steps

To a solution of 9 (1.15 g, 2.36 mmol) in methanol (40 mL) was added potassium carbonate (389 mg, 2.81 mmol). After 3.5 h, saturated ammonium chloride (45 mL) and saturated brine (25 mL) were added, the mixture was extracted with ethyl acetate (3×60 mL), dried (magnesium sulfate), filtered, concentrated, and chromatographed on a 14 cm tall×41 mm diameter silica gel column eluting with 4:1 ethyl acetate:hexane to afford 10 (708 mg,81%).

Provenance & Evidence