N-methyl-N-methyloxy-2-benzyloxycarbonylamino-5-isobutyloxybenzamide → N-methyl-N-methyloxy-2-amino-5-isobutyloxybenzamide

Participants

Reaction Steps

N-Methyl-N-methyloxy-2-benzyloxycarbonylamino-5-isobutyloxybenzamide (1.0 g) was dissolved in a mixture of ethyl acetate (10 ml) and methanol (10 ml). To the solution was added 10% palladium-carbon (0.2 g). The mixture was stirred for two hours at room temperature under hydrogen atmosphere. The reaction mixture was subjected to filtration. From the filtrate, the solvent was distilled off to leave N-methyl-N-methyloxy-2-amino-5-isobutyloxybenzamide as a yellow oily product (0.6 g).

Provenance & Evidence