Methanol → HCID 53786103, compound

Participants

Reaction Steps

To a methanol (20 ml) solution of 2-amino-3′-tritylaminomethyl-5-chlorobenzophenone (2 g) was added sodium borohydride (227 mg). The mixture was stirred for 3 hours at room temperature, to which was added acetic acid ethyl ester (100 ml). The mixture was washed with water and then dried over anhydrous MgSO4. The solvent was then distilled off, and the residue was purified by means of a silica gel column chromatography to give the-object 2-amino-5-chloro-α-(3-tritylaminomethylphenyl)benzyl alcohol (2.0 g) as a colorless oily product.

Provenance & Evidence