Cyclopentylamine → 5,6-Dimethyl-2-(cyclopentylamino)-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine hydrochloride

Beteiligte Stoffe

Reaktionsschritte

After cyclopentylamine(0.27 ml, 2.7 mmol) and triethylamine(0.38 ml, 2.7 mmol) were added to a solution of 2-chloro-5,6-dimethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl) pyrimidine(0.5 g, 1.8 mmol) in dimethylformamide, 270 mg of the titled compound was obtained in accordance with the same procedure as in Example 1.

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