Potassium Carbonate → HCID 69690148, compound

Participants

Reaction Conditions

Reaction Steps

Potassium carbonate (296 mg) was added to a solution of 200 mg of ethyl 3-butyrylamino-4-nitrobenzoate and 154 mg of 2-cyanobenzyl bromide in N,N-dimethylformamide, and the mixture was stirred at 20° C. for 3 hours. The reaction mixture was extracted with ethyl acetate and with water. The organic layer was washed with water and with a sodium chloride aqueous solution, and was then dried over magnesium sulfate. The solvent was distilled off under reduced pressure to give 330 mg of yellow oil of ethyl 3-[N-(2-cyanobenzyl)butyrylamino]-4-nitrobenzoate.

Provenance & Evidence