HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-chloro-4-hydroxyphenylacetate → 3-Chloro-4-(3'-methyl-4'-isopropoxybenzyloxy) phenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-chloro-4-hydroxyphenylacetate | HCID 92625 | — |
| Reactant | 3-Methyl-4-isopropoxybenzyl chloride | HCID 12347937 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Chloro-4-(3'-methyl-4'-isopropoxybenzyloxy) phenylacetic acid | HCID 12347958 | 35.2% |
Reaction Steps
3-chloro-4-(3'-methyl-4'-isopropoxybenzyloxy) phenylacetic acid was prepared in 35.2% yield, m.p. 104°-105° C. (methanol) by reaction of 3-methyl-4-isopropoxybenzyl chloride with methyl 3-chloro-4-hydroxyphenylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221919 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-d8e0b81e2c234c8b87680ef0a112eb96 |
| Source note | uspto-grants-1980_09 |