Sodium Methoxide → HCID 18316937, compound

Participants

Reaction Steps

The process of claim 5 wherein 1-(3-pyridinyl)-ethanone-O-[(4-methylphenyl)-sulfonyl]-oxime is reacted with methanol and sodium methylate to form 3-(2H-azirin-3-yl)-pyridine, reacting the latter without isolating it with oxalic acid to obtain β,β-dimethyloxy-3-pyridine-ethanamine, reacting the latter without isolating it with formamide to obtain N-[β,β-dimethoxy-2-(3-pyridinyl)-ethyl]-formamide and subjecting the latter without isolating it to cyclization by heating to obtain a compound of formula I.

Provenance & Evidence