HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Hydroxypipecolic acid → Methyl L-prolinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Hydroxypipecolic acid | HCID 151730 | — |
| Reactant | 5-Methoxypipecolic acid methyl ester | HCID 57063014 | — |
| Product | Methyl L-prolinate | HCID 853477 | — |
| Product | 5-Methoxyproline | HCID 70588130 | — |
Reaction Steps
By substituting 5-methoxypipecolic acid methyl ester [prepared from 5-hydroxypipecolic acid by the procedure described in J. Chem. Soc. 429 (1945) for 5-methoxyproline] for the L-proline methyl ester in the procedure of Example 18, 2,3-dehydro-1-(3-acetylthio-1-oxopropyl)-5-methoxypipecolic acid is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221912 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-287b883a75be461c8d84b27216c1c6b0 |
| Source note | uspto-grants-1980_09 |