Methylamine → HCID 178483000, compound

Participants

Reaction Steps

To a solution of methylamine in methanol (2.0M, 5 mL) was added 2-(2-methyl-4-nitrophenylimino)-4-(chloromethyl)-1,3-thiazolidine (prepared in a manner analogous to that described in Method C2a; 0.040 g, 0.140 mmol) and the resulting mixture was stirred at room temp for 72 h. The mixture was concentrated under reduced pressure and the resulting residue was purified by flash chromatography (5% MeOH/CH2Cl2) to give 2-(2-methyl-4-nitrophenylimino)-4-(N-methylaminomethyl)-1,3-thiazolidine as a solid (0.014 g, 35%).

Provenance & Evidence