2-Methyl-4-nitrophenyl isothiocyanate → HCID 22951289, compound

HRID 276320Notes

Reaction equation

HRID 276320 reaction equation
[Cl-].Cl[CH2:3][CH2:4][NH2+:5][CH:6]([CH2:9][CH3:10])[CH2:7][CH3:8].[CH3:11][C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[N:21]=[C:22]=[S:23]>>[CH3:11][C:12]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:13]=1[N:21]=[C:22]1[N:5]([CH:6]([CH2:9][CH3:10])[CH2:7][CH3:8])[CH2:4][CH2:3][S:23]1

Participants

3

Reactant 2

HCID 1456212-Methyl-4-nitrophenyl isothiocyanateHCID 86590172HCID 86590172, compound

Product 1

HCID 22951289HCID 22951289, compound

Procedure

3-Pentylamine was converted to N-(2-hydroxyethyl)-N-(3-pentyl)amine according to Method B5a. The amine was reacted with SOCl2 according to Method B7a to give N-(2-chloroethyl)-N-(3-pentyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate according to Method C1a to give to give 2-(2-methyl-4-nitrophenylimino)-3-(3-pentyl)-1,3-thiazolidine.

Workup

  1. customto give

Sources & evidence

ORD record
ord-563be479a32745b692ab8c0006264a22
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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