2-Chloroethylamine → HCID 18316310, compound

HRID 276331Notes

Reaction equation

HRID 276331 reaction equation
Cl[CH2:2][CH2:3][NH2:4].[CH3:5][C:6]1[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:7]=1[N:15]=[C:16]=[S:17]>>[CH3:5][C:6]1[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:7]=1[N:15]=[C:16]1[N:4]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[CH2:3][CH2:2][S:17]1

Participants

3

Reactant 2

HCID 133692-ChloroethylamineHCID 1456212-Methyl-4-nitrophenyl isothiocyanate

Product 1

HCID 18316310HCID 18316310, compound

Procedure

N-(2-Hydroxyethyl)aniline was reacted with SOCl2 according to Method B7a to give N-2-chloroethyl)anilinium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate according to Method C1a to afford 2-(2-methyl -4-nitrophenylimino)-3-phenyl-1,3-thiazolidine.

Sources & evidence

ORD record
ord-9fb628b5b47e4dce818554ec18bfb43f
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

Loading…