HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-4-nitrophenyl isothiocyanate → 2-(2-Methyl-4-nitrophenylimino)-3-(cyclopropylmethyl)-1,3-thiazolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-4-nitrophenyl isothiocyanate | HCID 145621 | — |
| Reactant | N-cyclopropylmethyl-N-(2-chloroethyl)ammonium chloride | HCID 18316126 | — |
| Product | 2-(2-Methyl-4-nitrophenylimino)-3-(cyclopropylmethyl)-1,3-thiazolidine | HCID 18316268 | — |
Reaction Steps
2-Hydroxyethylamine was reacted with cyclopropylmethyl bromide according to Method B2a to give N-cyclopropylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclopropylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-(cyclopropylmethyl)-1,3-thiazolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-9f132cf4355a403c8cebb0145c84aaa3 |
| Source note | uspto-grants-2002_03 |