化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → N-cyclobutylmethyl-N-(2-chloroethyl)ammonium chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-((Cyclobutylmethyl)amino)ethanol | HCID 18316306 | — |
| 生成物 | N-cyclobutylmethyl-N-(2-chloroethyl)ammonium chloride | HCID 18316353 | — |
反応手順
2-Hydroxyethylamine was reacted with cyclobutylmethyl bromide according to Method B2a to give N-cyclobutylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclobutylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 3,4-dichlorophenyl isothiocyanate to give 2-(3,4-dichlorophenylimino)-3-(cyclobutylmethyl)-1,3-thiazolidine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06353006B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-64e8394378e3467ab90beae665901181 |
| 出典メモ | uspto-grants-2002_03 |