HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 2-((Cyclobutylmethyl)amino)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | (Bromomethyl)cyclobutane | HCID 2734658 | — |
| Product | 2-((Cyclobutylmethyl)amino)ethanol | HCID 18316306 | — |
Reaction Steps
2-Hydroxyethylamine was reacted with cyclobutylmethyl bromide according to Method B2a to give N-cyclobutylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclobutylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 3-chloro-2-methylphenyl isothiocyanate to give 2-(3-chloro-2-methylphenylimino)-3-(cyclobutylmethyl)-1,3-thiazolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-067d4530617b437f8db6e8b1b2fde352 |
| Source note | uspto-grants-2002_03 |