HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylethanolamine → N-(2-Chloroethyl)benzylamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylethanolamine | HCID 4348 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | N-(2-Chloroethyl)benzylamine hydrochloride | HCID 22712 | — |
Reaction Steps
2-Hydroxyethylamine was reacted with benzyl bromide according to Method B2a to give N-benzyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-benzyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 3,4-dichlorophenyl isothiocyanate to give 2-(3,4-dichlorophenylimino)-3-benzyl-1,3-thiazolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-17eb7cf884c041c8b29a601d984a8118 |
| Source note | uspto-grants-2002_03 |