2,3-Dichlorophenyl Isothiocyanate → 2-(2,3-Dichlorophenylimino)-3-(cycloheptylmethyl)-1,3-thiazolidine

HRID 276425Notes

Reaction equation

HRID 276425 reaction equation
[Cl-].[CH:2]1([CH2:9][NH2+:10][CH2:11][CH2:12]Cl)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[Cl:14][C:15]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=1[N:22]=[C:23]=[S:24]>>[Cl:14][C:15]1[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=1[N:22]=[C:23]1[N:10]([CH2:9][CH:2]2[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]2)[CH2:11][CH2:12][S:24]1

Participants

3

Reactant 2

HCID 27962812,3-Dichlorophenyl IsothiocyanateHCID 18316106N-cycloheptylmethyl-N-(2-chloroethyl)ammonium chloride

Product 1

HCID 183164952-(2,3-Dichlorophenylimino)-3-(cycloheptylmethyl)-1,3-thiazolidine

Procedure

2-Hydroxyethylamine was reacted with cycloheptylmethyl bromide according to Method B2a to give N-cycloheptylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cycloheptylmethyl -N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2,3-dichlorophenyl isothiocyanate to give 2-(2,3-dichlorophenylimino)-3-(cycloheptylmethyl)-1,3-thiazolidine.

Sources & evidence

ORD record
ord-c641b4472d3948cd983f05696b2a1e99
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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