化工社化工社 化学情報印刷レポート · 研究参考用
4-Nitro-1-naphthylamine → HCID 178445847、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Nitro-1-naphthylamine | HCID 13057 | — |
| 反応物 | (+)-L-Leucine methyl ester | HCID 65105 | — |
| 反応物 | L-Leucinol | HCID 111307 | — |
| 反応物 | 4-Nitro-1-naphthyl isothiocyanate | HCID 18316079 | — |
| 生成物 | HCID 178445847 | HCID 178445847 | — |
反応手順
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was made from (L)-leucine methyl ester as described in Method B1b. 4-Nitro-1-naphthylamine was converted to 4-nitro-1-naphthyl isothiocyanate according to Method A2b. 4-Nitro-1-naphthyl isothiocyanate was reacted with (1S)-1-(hydroxymethyl)-3-methylbutylamine to Method C2a to give (4S)-2-(4-nitro-1-naphthylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to give (4S)-2-(4-nitro-1-naphthylimino)-3,4-diisobutyl-1,3-thiazolidine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06353006B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-95adf840d7bd42c58444000ce7f94ab8 |
| 出典メモ | uspto-grants-2002_03 |