HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 178428756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Methyl-4-nitrophenyl isothiocyanate | HCID 145621 | — |
| Reactant | D-Valinol | HCID 6950587 | — |
| Product | HCID 178428756 | HCID 178428756 | — |
Reaction Steps
(1R)-1-Isopropyl-2-hydroxyethylamine was reacted with SOCl2 followed by 2-Methyl-4-nitrophenyl isothiocyanate according to Method C2a to give (4R)-2-(2-methyl-4-nitrophenylimino)-4-isopropyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to afford (4R)-2-(2-methyl -4-nitrophenylimino)-4-isopropyl-3-isobutyl-1,3-thiazolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-e57f662bf6bf414e97d9c41c6fe6e8a0 |
| Source note | uspto-grants-2002_03 |