HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 9-(2-Methyl-4-nitrophenylimino)-1-aza-8-thiabicyclo[4.3.0]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 2-Methyl-4-nitrophenyl isothiocyanate | HCID 145621 | — |
| Reactant | Methyl pipecolinate | HCID 3463753 | — |
| Reactant | HCID 178478436 | HCID 178478436 | — |
| Product | 9-(2-Methyl-4-nitrophenylimino)-1-aza-8-thiabicyclo[4.3.0]nonane | HCID 18316305 | — |
Reaction Steps
2-Piperidenemethanol was made from methyl pipecolinate as described in Method B1b. The 2-hydroxyethylamine was converted to 2-chloromethylpiperidinium chloride according to Method B7a. 2-Methyl4-nitrophenyl isothiocyanate was reacted with 2-chloromethylpiperidinium chloride according according to Method C1a to give 9-(2-methyl-4-nitrophenylimino)-1-aza-8-thiabicyclo[4.3.0]nonane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06353006B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-c951ff5debe4466ebad410dd29a6a027 |
| Source note | uspto-grants-2002_03 |