3-Bromo-2-methyl-1-propene → HCID 86590177, compound

HRID 276510Notes

Reaction equation

HRID 276510 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]1[NH:16][CH2:15][CH:14]([CH3:17])[S:13]1.[CH3:18][C:19](=[CH2:22])[CH2:20][Br:21]>>[BrH:21].[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]1[N:16]([CH2:20][C:19]([CH3:22])=[CH2:18])[CH2:15][CH:14]([CH3:17])[S:13]1

Participants

3

Reactant 2

HCID 3577853-Bromo-2-methyl-1-propeneHCID 178428747HCID 178428747, compound

Product 1

HCID 86590177HCID 86590177, compound

Procedure

2-Hydroxypropylamine was converted to 2-chloropropylammonium chloride according to Method B7a. 2-Methyl-4-nitrophenyl isothiocyanate was reacted with 2-chloropropylammonium chloride according to Method C1a to give 2-(2-methyl-4-nitrophenylimino)-5-methyl-1,3-thiazolidine. The thiazolidine was reacted with 2-methylprop-2-en-1-yl bromide according to Method D2g to afford 2-(2-methyl-4-nitrophenylimino)-3-(2-methylprop-2-en-1-yl)-5-methyl-1,3-thiazolidine HBr salt.

Sources & evidence

ORD record
ord-12438802565c4c5abb6d852d9f3106df
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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