Ethylene Oxide → HCID 178428574, compound

HRID 276522Notes

Reaction equation

[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]=[C:10]1[NH:14][CH2:13][C:12]([CH3:16])([CH3:15])[S:11]1.C1OC1>>[ClH:1].[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]=[C:10]1[NH:14][CH2:13][C:12]([CH3:16])([CH3:15])[S:11]1

Participants

Reactant 2

HCID 6354Ethylene Oxide

HCID 178428573HCID 178428573, compound

Product 1

HCID 178428574HCID 178428574, compound

Procedure

2-Methyl-2-hydroxypropylamine was reacted with SOCl2 followed by 2,3-dichlorophenyl isothiocyanate according to Method C2f to afford 2-(2,3-dichlorophenylimino)-5,5-dimethyl-1,3-thiazolidine. 2-(2,3-Dichlorophenylimino)-5,5-dimethyl-1,3-thiazolidine was reacted with ethylene oxide according to Method B5b to afford 2-(2,3-dichlorophenylimino)-5,5-dimethyl-1,3-thiazolidine HCl salt.

Sources & evidence

ORD record: ord-86e6dfe8bead41e19692bdc1b3461a19
Source dataset: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06353006B1

Reaction notes

Loading…